PEG

Biotin-PEG4-methyltetrazine is a click chemistry biotinylation reagent that can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TAMRA-PEG4-Tetrazine is a tatrazine attached tetramethylrhodamine (TAMRA) dye. Rhodamine is a commonly used red fluorescent dye tracer in biology for staining cells, tissues, biomarkers or nanoparticles. It has peak fluorescence emission at 572-575 nm. Tetrazin demonstrates exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctene (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PNB Ester contains two reactive substituents. The PNB ester is reactive with amine groups. TCO group can participate in Click Chemistry reactions with tetrazine and can be used to label antibodies and proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-Sulfo-NHS Ester is a water-soluble amine-reactive membrane impermeable labeling reagent. It will be chosen for applications that are intolerant of organic solvents and can be used to efficiently label antibodies, proteins and any other primary amine-containing macromolecules. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG4-NHS Ester is a click chemistry crosslinker containing a methyltetrazine group. The hydrophilic PEG spacer improves water solubility and is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond. Methyltetrazine enable click chemistry with TCO (trans-cycloctene). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Tetrazine-NHS Ester is a NHS activated tetrazine linker. NHS ester is very reactive with amine containing molecule. Tetrazine enable fast click reaction with TCO (trans-cycloctene). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

PC Azido-PEG3-NHS carbonate ester is a photocleavable linker. It can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG4-Picolyl azide is a biotin reagent which can be conjugated with alkyne-containing biomolecules. This biotin reagent incorporates a copper-chelating motif that dramatically accelerates the Cu(I)-catalyzed Click Chemistry. The use of Biotin Picolyl Azide instead of conventional Biotin Azide allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG3-SS-azide has a cleavable disulfide bond and a terminal azide group. The biotin group is used for protein conjugation and can also be used for chemical labeling. The azide group can participate in copper-catalyzed Click Chemistry reactions with alkyne moieties. The hydrophilic PEG linker increases the compound's water solubility in aqueous compounds. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.