PEG

Azide-PEG-amine TFA salt, MW 5,000 is a PEGylation reagent with azide and amine end groups. The azide can participate in click chemistry with alkyne either by copper catalyzed or copper free reaction. The amine can react with activated NHS ester to form a stable amide bond. Reagent grade, for research purpose.

HO-PEG-amine, MW 1,000 is an amino PEG with hydroxyl moiety group. The amine group is reactive with activated NHS ester to form a stable amide bond. The hydroxyl can be further derivatized. Reagent grade, for research purpose.

PC-Biotin-PEG4-PEG4-alkyne is useful for introducing a biotin moiety to azide-containing biomolecules using Cu(I)-catalyzed Click Chemistry. The extended hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Captured biomolecules can be efficiently photoreleased using near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-Boc-Aminooxy-PEG2-amine contains a Boc-protected aminooxy group and a free amino(NH2) group. Amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc- aminooxy can be deprotected under mild acidic conditions and then reacts with an aldehyde to form a linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Aminooxy-PEG2-azide contain an azide and an aminooxy group. The aminooxy group reacts with an aldehyde or ketone group to form a oxime linkage. The azide group enables Click Chemistry. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.

Amino-PEG1-Amine is a water soluble PEG linker containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

PC-Biotin-PEG4-NHS carbonate is a unique amine reactive, photocleavable biotin reagent that is useful for introducing a biotin moiety to amine-containing biomolecules. The NHS carbonate portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG4-(CH2)3-methyl ester consists of a propargyl group and a methyl ester. The propargyl group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions to form a stable triazole linkage. Under strong basic condition, methyl ester can be hydrolyzed. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

PEG16 is a polymeric structure consisting of ethylene glycol units and two terminal hydroxyl groups. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. The water solubility properties of the PEG linker are enhanced with longer PEG chains. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.