PEG

Dde Biotin-PEG4-Picolyl azide is a cleavable biotin reagent containing a picolyl azide moiety which can be conjugated with alkyne-containing biomolecules. This biotin reagent incorporates a copper-chelating motif that dramatically accelerates the Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Dde protecting group allows efficient release of captured biotinylated molecules from streptavidin under mild conditions with hydrazine. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG10-Tos is a PEG linker containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Aminooxy-PEG-OH, MW 2,000 is a PEGylation reagent containing an aminooxy group and a hydroxyl group. The aminooxy can undergo oxime ligation with an aldehyde or ketone. Hydroxyl group is readily available for further derivatization. Reagent grade, for research purpose.

t-Boc-Aminooxy-PEG4-CH2CO2H is a crosslinking reagent with a Boc-protected aminooxy group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU). The Boc-protected amine can be deprotected under mild acidic conditions. PEG4 spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

PC Mal-NHS carbonate ester is a photocleavable linker containing a Maleimide and an NHS ester groups. The maleimide group can react with thiol groups between pH 6.5 to 7.5. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

HO-PEG-amine, MW 5,000 is a PEGylation reagent with a terminal amine which can be reacted with an activated NHS ester in an aqueous solution. The reactive hydroxyl group is used for further modification. Reagent grade, for research purpose.

m-PEG-Mal, MW 5,000 is a maleimide polyPEG which is reactive with thiol group via Michael addition at pH 6.5 to 7.5. Reagent grade, for research purpose.

Amino-PEG25-acid is a aqueous soluble molecule containing an amino group with a terminal carboxylic acid. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Tos-PEG5-CH2CO2H is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.