PEG

Biotin-PEG2-iodide is abiotin compound that can reactive with nucleophiles. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG7-amine HCl salt is an aqueous soluble amine-containing click chemistry crosslinker. Methyl group improves the stability and hydrophilic PEG spacer increases water-solubility. The amine (NH2) group is reactive with carboxylic acid containing molecule in the presence of reagnet such as EDC or HATU. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene) Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG12-NHS Ester is a monodisperse PEG linker which enable free copper click chemistry with N3 group. NHS ester moiety can react specifically and efficiently with primary amines to form a covalent amide bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

4-Hydroxy-thalidomide is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTACs. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

dBET1 is a PROTAC compound comprised of BET bromodomain antagonist (+)-JQ1 linked to a cereblon E3 ubiquitin ligase ligand. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG11-DBCO is a TCO reactive reagent with a DBCO group and water-soluble PEG spacer. This reagent can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG-silane, MW 5,000 is a surface reactive PEG polymer for biotinylation of glass, silica and other substance. Reagent grade, for research purpose. This product is hygroscopic; excessive moisture may affect the stability of the compound.

m-PEG-silane, MW 5,000 is a silane PEG polymer for surface modification through reaction between hydroxyl group and ethoxyl silane. The PEG spacer enhances water solubility of the compound. Reagent grade, for research purpose.

Biotin-PEG8-amine is a biotinylation reagent with a terminal primary amine group. The amine group can be coupled to carboxyl groups or 5'phosphate groups to form stable amide bonds. PEG8 arm increases aqueous solubility of the molecules conjugated to the biotin compound and also helps to minimize steric hindrance involved with the binding to avidin molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.