PEG

DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG6-DBCO is a monodisperse PEG reagents which can enable copper-free Click Chemistry through the reaction of DBCO with azide. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(S, R, S)-AHPC-PEG4-Azide is a click chemistry PROTAC linker that incorporatess an E3 ligase ligand with a PEG4 arm to empower PROTAC research & discovery. The hydrophilic PEG spacer increases the solubility of a compound in aqueous media. Azide enable click chemistry with ALkyne or DBCO, BCN molecule. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(S, R, S)-AHPC-PEG4-acid is a synthetic PROTAC linker that incorporatess an E3 ligase ligand with a PEG4 arm to empower PROTAC drug research & discovery. It is reactive with amine containing molecule. The hydrophilic PEG spacer increases the solubility of a compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azide-PEG-CH2CO2H, MW 1,000 is a click chemistry polyPEG polymer, Azide is reactive with alkyne group, such as DBCO or BCN molecules via click chemistry. Carboxylic acid can conjugate with amine containing molecules such as protein, peptide in the presence of coupling reagent, HATU or EDC to form amide bond. Reagent grade, for research purpose.

Amino-PEG2-alcohol is a short PEG linker containing an amino group with a hydroxyl group. The amino (NH2) group is reactive with activated NHS esters, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG3-triethoxysilane is a PEG linker containing a triethoxysilane moiety. Triethoxysilane is commonly used for surface modifications. The hydrophilic PEG linkers increase the water solubility of a compound in aqueous media. The water solubility properties of the PEG linkers are enhanced with longer PEG chains. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG-acid, MW 1,000 is a linear heterobifunctional PEG derivative. The cyclooctyne DBCO is used for bioorthogonal reaction with azide molecule via Cu-free Click Chemistry (SPAAC). Reagent grade, for research purpose.