PEG

Aminooxy-PEG4-alcohol is an aqueous soluble PEG reagent. The aminooxy group can react with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.

Tos-PEG6-CH2CO2tBu is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Amino-PEG2-t-Boc-Hydrazide is a PEG reagent containing an amino group and a Boc-protected hydrazide. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Hydroxy-PEG2-methyl ester is a PEG linker containing a hydroxyl group and a methyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Methyl ester can be hydrolyzed under strong basic condition. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG-NH2, MW 10,000 is a PEGylation reagent with a free amine terminus which can couple with an activated NHS ester to form a stable amide bond in bioconjugation. Reagent grade, for research purpose.

Amine-PEG-amine, MW 2,000 is a homobifuctional diamines polyPEG. This compound is useful for modification of biological molecules by covalent conjugation as a strategy to overcome disadvantages associated with some biopharmaceuticals. Reagent grade, for research purpose.

Amine-PEG-amine, MW 3,400 is a homofunctionalized PEGylation reagent with two terminal amines. The amines can react with activated NHS esters to form a stable amide bond. Reagent grade, for research purpose.

Amine-PEG-amine, MW 5,000 is a PEG polymer with two terminal amines. The amine is reactive with NHS ester to form a stable amide bond. The hydrophilic polyPEG increases the water solubility of the compound. Reagent grade, for research purpose.

Amine-PEG-CH2OOH, MW 2,000 is a PEGylation reagent containing one carboxylic acid group. The amine group is reactive with activated NHS esters. The carboxylic acid can react with primary amines in the presence of activator, such as EDC or HATU, to form a stable amide bond. The PEG polymer is aqueous soluble. Reagent grade, for research purpose.