PEG

N-Mal-N-bis(PEG2-amine) TFA salt is a branched maleimide linker that is reactive with a thiol(SH) group to form a covalent bond. The amino(NH2) is reactive withactivated NHS esters or carboxylic acid in the presence of EDC or HATU. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Mal-NH-ethyl-SS-propionic acid is a cleavabe, Maleimide linker. The maleimide group will react with thiol groups to form a covalent bond, enabling the connection of biomolecule to a thiol. Terminal carboxylic acids can react with primary amine groups using activators such as EDC and HATU to from stable amide bonds. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-Mal-N-bis(PEG4-amine) TFA salt is a branched PEG linker with a terminal maleimide group and two terminal amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

4-Azide-TFP-Amide-SS-propionic acid contains an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The carboxylic acid can be reacted with amines in the presence of an activator to form an amide bond. The disulfide bond can be cleaved via reducing agents. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-Boc-N-Amido-PEG5-Ms is a PEG linker that contains a Boc protecting group and a mesyl group. The t-Boc group can be removed under acidic conditions to produce a reactive free amine. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases the water solubility of the compound. Longer PEG chains increase the water solubility properties of the compound. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG-Tos, MW 2,000 is a tosylated PEG polymer for nucleophilic SN2 substitution reaction for further derivatization. Reagent grade, for research purpose.

Amino-PEG11-alcohol is a crosslinking reagent consisting of an amino (NH2) group with a hydroxyl(OH) group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydroxyl (OH) enables further derivatization. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Cbz-N-amido-PEG20-acid is a PEG linker containing a Cbz-protected amino group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected by acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(Azido-PEG4)-N-bis(PEG4-amine) is a 3-arm PEGylation reagent containing an amino group with two azide groups. The amino group is reactive with carboxylic acids, activated NHS esters. . The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.