PEG

m-PEG4-SPDP is a pyridyldithio functional linker which is reactive with thiol, sulfhydryl, or mercapto to form a cleavable disulfide bond. The PEG4 chain increases the hydrophilicity of the compound.

Fmoc-Glu(OtBu)-OH

Fmoc-Glu(OAll)-OH

Palmitate-PEG-mal, MW 1,000

N-Mal-N-bis(PEG4-t-butyl ester) serves as a branched PEG linker containing two t-butyl ester groups that can be deprotected under acidic conditions, maleimide for covalently binding free thiols on cysteine residues of proteins, and PEG spacers for enhanced hydrophilicty.

BP Lipid 409 is an analog of LP01 featuring a multichargeable methyl piperazine head group. This cyclic amine functionality was designed to fine-tune the properties of this popular lipid while maintaining the unsaturated and branched lipid tails, and the biodegradable ester and carbonate linkages. This compound may be used as a novel component in lipid nanoparticle (LNP) formulations. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

4-(2-Pyridinyldithio)-2-sulfobutanoic acid

Pteroic acid

NH-bis(PEG8-Boc) serves as a PEG linker including two terminal Boc groups that can be deprotected under mild acidic conditions to form the free amine as well as a central amine group with PEG chains on either side for improved water solubility of the compound.