PEG

Tri-GalNAc -COOH

Also known as 1,2-Dipalmitoyl-Sn-Glycero-3-Succinate

15(Z)-Tetracosenol

Benzyloxy carbonyl-PEG12-t-butyl ester is a heterobifunctional linker comprised of a benzyloxy carbonyl where the benzyl protecting group can be removed by hydrogenolysis and t-butyl ester can be deprotected under acidic conditions. The PEG12 chain improves the molecule's hydrophilicity.

N-Mal-N-bis(PEG8-NH-Boc) serves as a branched PEG linker consisting of two Boc groups which can be removed under acidic conditions to free the amine for further reactions. The maleimide attached to the central amine of the molecule can react directly with thiol-bearing entities to form a covalent bond.

Methyltetrazine-PEG3-Iodoacetamido comprises of a methyltetrazine that enables fast click chemistry with TCO (trans-cycloctene), and the methyl group enhances the stability of the tetrazine moiety. The iodoacetamido moiety is commonly used to bind covalently with the thiol group of cysteine so the protein cannot form disulfide bonds.

Methyltetrazine-PEG3-Iodoacetamido consists of a click chemistry methyltetrazine handle that speedily reacts with TCO (trans-cycloctene), and the methyl group improves the tetrazine's stability. The iodoacetamido moiety may be employed to bind covalently with the thiol group of cysteine to prevent disulfide bridges in proteins.

Biotin-PEG4-sulfo-Maleimide is comprised of a terminal biotin and a maleimide group that will specifically and efficiently react with thiols to form thioether bonds.

mPEG-TCO, MW 2,000 is a polyPEG reagent comprised of a TCO group that specifically and efficiently reacts with tetrazine. The hydrophilic 2k PEG polymer increases the solubility of compounds in aqueous media.