PEG

DBCO-PEG4-C3-sulfonic acid serves as a bifunctional PEG linker. The DBCO click chemistry handle conjugates with azides on target molecules to form stable triazole linkages. The sulfonic acid can participate in esterification, halogenation and displacement reactions.

An ionizable lipid featuring biodegradable ester linkages and monounsaturated palmitoleic acid tails. These lipids may be formulated into lipid nanoparticles for drug delivery research. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Cbz-GGFG-Bn, as a potent and selective mTORC1 signaling inhibitor, plays a crucial role as a cytotoxic payload in the development of antibody-drug conjugates (ADCs). Reagent grade, for research purpose.

Propargyl-PEG-NHS ester, MW 2,000 serves as a polyPEG linker with a 2k PEG polymer for improved water-solubility and a terminal NHS ester to perform facile reactions with amine groups of molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

bis-Mes-PEG, MW 2,000 functions as a PEG polymer containing two terminal sulfonate ester group that can react with a nucleophile. The 2k polyPEG units elevate the hydrophilicty of the compound and may aid in optimizing DMPK properties. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 419 is an ionizable lipid featuring a unique azetidine head group and two unsaturated fatty acid tails. Additional features include three biodegradable ester linkages and polar hydroxyl group at the terminal position of the head group. This compound may be used in the formulation of lipid nanoparticles (LNP's) for delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

mPEG-TCO, MW 10,000 is a polyPEG reagent consisting of a TCO group that specifically and efficiently reacts with tetrazine. The hydrophilic 10k PEG polymer improves the solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(1,3-dioxoisoindolin-2-yl)-PEG3-amine serves as a unique PROTAC linker, featuring a thalidomide analog, hydrophilic PEG spacer, and free amine to readily react with an activated NHS ester. Thalidomide recruits E3 Ligase for the ubiquitinylation and subsequent destruction of a given protein. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

An azide-PEG functionalized analog of the ionizable lipid ALC-0315 used in mRNA delivery applications. The azide functionality may allow for bioconjugation or surface decoration. Additional PEG chaing lengths available upon request. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.