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    Results for PEG ( 4422 )

      • Ref: BP-42160
        Sizes: 1 MG, 5 MG, 10 MG
        From: €570.00

        VEGFR-2-IN-39 is a PROTAC designed to specifically target VEGFR-2, exhibiting low toxicity. This compound effectively inhibits the proliferation of EA.hy926 cells, a line derived from human umbilical vein endothelial cells, in a concentration-dependent manner. Its structural composition enables effective interaction with VEGFR-2, making it useful for studying vascular-related pathways.

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      • Ref: BP-42162
        Sizes: 1 MG, 5 MG
        From: €795.00

        PROTAC MDM2 Degrader-1 employs PROTAC technology to target and degrade MDM2. It consists of a potent MDM2 inhibitor linked to a ligand that interacts with E3 ubiquitin ligase, facilitating selective protein degradation. This structural design enhances the compound's ability to modulate protein levels effectively through targeted ubiquitination mechanisms.

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      • Ref: BP-42163
        Sizes: 1 MG, 5 MG
        From: €645.00

        PROTAC BRD9 Degrader-4 is a bifunctional degrader targeting BRD9, designed for use in cancer research. Its structural components enable effective protein degradation, facilitating the study of BRD9's role in cancer biology.

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      • Ref: BP-42164
        Sizes: 1 MG, 5 MG, 10 MG
        From: €480.00

        PROTAC BET Degrader-1 is a bifunctional molecule that links Cereblon and BET ligands, effectively reducing the levels of BRD2, BRD3, and BRD4 proteins. Its functional groups enable targeted protein degradation at low concentrations

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      • Ref: BP-42165
        Sizes: 1 MG, 5 MG, 10 MG
        From: €480.00

        PROTAC BRD4 Degrader-1 is a bifunctional molecule linking Cereblon and BRD4 ligands, designed to target and degrade BRD4 protein. Its structure enables effective reduction of BRD4 levels and modulation of c-Myc expression.

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      • Ref: BP-42166
        Sizes: 1 MG, 5 MG
        From: €1,020.00

        PROTAC ERα Degrader-1 is a molecule consisting of an E3 ligase ligand, a linker, and an estrogen receptor-alpha (ERα) targeting group, facilitating targeted degradation of ERα.

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      • Ref: BP-42167
        Sizes: 1 MG, 5 MG
        From: €1,125.00

        HDAC6 Degrader-1 is a PROTAC that utilizes Nexturastat A as a selective HDAC6-binding component, combined with a linker and an E3 ligase-recruiting ligand. This structure promotes targeted degradation of HDAC6, offering strong selectivity over other HDAC enzymes and effectively inhibiting cell proliferation.

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      • Ref: BP-42168
        Sizes: 1 MG, 5 MG, 25 MG, 10 MG
        From: €315.00

        MI-389 is a PROTAC designed to degrade the translation termination factor GSPT1. It disrupts a critical target shared across various AML and ALL cell lines, with its activity dependent on CRL4 CRBN E3 ligase recruitment.

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      • Ref: BP-42169
        Sizes: 1 MG
        From: €1,470.00

        KTX-582 is a potent PROTAC targeting the degradation of IRAK4 and Ikaros. It promotes apoptosis in MYD88 mutant cell lines and demonstrates efficacy in inducing tumor regression in lymphoma models.

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