PEG

Hydroxy-PEG5-CH2CO2tBu is a PEG linker containing a hydroxyl group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Amino-PEG4-CH2CO2H is a PEG linker containing an amino group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Iodoacetamido-PEG8-t-butyl ester is a PEG reagent containing an Iodoacetamide group and a t-butyl ester. The iodoacetamide group is an alkylating agent that can be used to bind covalently with the thiol group. The t-butyl ester groups can be deprotected under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG5-amine is a propargyl linker that is commonly used as a Click Chemistry reagent for copper-catalyzed reactions with azides. The amine moiety reacts with carboxylic acids, activated NHS esters and other carbonyl compounds. The PEG spacer helps improve the water solubility of the molecule in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-PEG4-CH2CO2-t-butyl ester is a PEG reagent containing an azide group and a t-butyl protected carboxyl group. The azide group enables Click Chemistry. The protected carboxyl group (COOH) prevents self coupling or polymerization under standard acid/amine or acid/hydroxyl coupling conditions. t-butyl ester can be deprotected by acidic or basic hydrolysis. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin hydrazide is a hydrazide-activated biotinylation reagent used to label glycoproteins, carbohydrate-containing compounds that have oxidizable sugars or aldehydes. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG4-amine is a popular biotinylation reagent with PEG spacer. It can be coupled to carboxyl groups or 5'phosphate groups to form stable amide bonds. PEG spacer increases aqueous solubility of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG6-amine is a PEGylated biotinylation reagent that can react with NHS ester or carboxutlic acid. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG8-NHS ester is an amine reactive biotinylation reagent that can conjugate with amino molecule. The NHS moiety reacts specifically and efficiently with lysine and N-terminal amino groups at pH 7-9. The hydrophilic PEG spacer increases aqueous solubility. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.