PEG

Propargyl-PEG12-OH (Legacy Tebubio ref. 282T16596). Propargyl-PEG12-OH is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG2-Ms (Legacy Tebubio ref. 282T16600). Propargyl-PEG2-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG3-acid (Legacy Tebubio ref. 282T16605). Propargyl-PEG3-acid is a non-cleavable (3-unit PEG) ADC linker and a PEG-based PROTAC linker, used to synthesize 6-OHDA-PEG3-yne, a compound containing 6-OHDA and Propargyl-PEG3-acid[1].

Propargyl-PEG4-Boc (Legacy Tebubio ref. 282T16618). Propargyl-PEG4-Boc is a PEG-based linker for PROTACs, joining two essential ligands to facilitate PROTAC molecule formation. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG4-NHS ester (Legacy Tebubio ref. 282T16628). Propargyl-PEG4-NHS ester is a non-cleavable 4-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.

Propargyl-PEG4-O-C1-Boc (Legacy Tebubio ref. 282T16629). Propargyl-PEG4-O-C1-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Propargyl-PEG4-O-C1-NHS ester (Legacy Tebubio ref. 282T16630). Propargyl-PEG4-O-C1-NHS ester, also known as compound 8, is a polyethylene glycol (PEG)-based linker that serves as a reactive functional group for the synthesis of proteolysis targeting chimeras (PROTACs).

Propargyl-PEG6-NH2 (Legacy Tebubio ref. 282T16643). Propargyl-PEG6-NH2 is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras] that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation via the ubiquitin-proteasome system within cells.

Propargyl-PEG7-alcohol (Legacy Tebubio ref. 282T16645). Propargyl-PEG7-alcohol is a PEG-based PROTAC linker utilized in the synthesis of PROTACs [1].