PEG

NH2-PEG2-C6-Cl (Legacy Tebubio ref. 282T40858). NH2-PEG2-C6-Cl is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by joining two essential ligands. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NH2-PEG2-C6-Cl hydrochloride (Legacy Tebubio ref. 282T40858L). NH2-PEG2-C6-Cl hydrochloride is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

Hydroxy-PEG4-methyl acetate (Legacy Tebubio ref. 282T40882). Hydroxy-PEG4-methyl acetate, a PEG-based linker compound, is utilized in PROTAC synthesis.

PEG2-Cl (Legacy Tebubio ref. 282T40894). PEG2-Cl is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amino-PEG4-C1-Boc (Legacy Tebubio ref. 282T40974). Amino-PEG4-C1-Boc is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands critical for PROTAC molecule formation, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG6-CH2COOH (Legacy Tebubio ref. 282T41011). Azido-PEG6-CH2COOH is a PEG-based linker for PROTACs, joining two essential ligands necessary for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Efpeglenatide (Legacy Tebubio ref. 282T64252). Efpeglenatide is a long-acting agonist of the glucagon-like peptide (GLP-1) receptor. efpeglenatide improves insulin sensitivity and slows weight loss in mice models of diabetes and obesity. efpeglenatide has been used in studies of type II diabetes.

Emapticap pegol (Legacy Tebubio ref. 282T64256). Emapticap pegol is a pro-inflammatory chemokine C-C motif ligand 2 (CCL2) inhibitor. emapticap pegol is also a 40-nucleotide oligonucleotide aptamer that exhibits different forms of Spiegelmers (L-RNA aptamers) in human (NOX-E36) and mouse (mNOX-E36).

Benzyloxy carbonyl-PEG4-Acid (Legacy Tebubio ref. 282T69729). Benzyloxy carbonyl-PEG4-acid is a linker with a benzyl protecting group and a carboxylic acid. The carboxylic acid can undergo reactions with primary amines with the help of activators (EDC or HATU). The benzyl protecting group can be removed via hydrogenolysis.