PEG

m-PEG4-t-butyl ester is a PEG linker containing a t-butyl ester. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG4-hydrazide is a PEG linker containing a hydrazide group. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG-NH2, MW 5,000 is an amine functional polyPEG which is reactive with NHS or carboxylic acid in the presence of HATU or EDC to form a stable amide linkage. Reagent grade, for research purpose.

TCO-NHS Ester is an popular reagent to label amine-containing compound or biomolecule, TCOI enable fast click chemistry with tetrazine. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG4-NHS Ester is a click chemistry crosslinker. This reagent can be used to label antibodies, proteins and other primary amine containing molecule. The hydrophilic PEG spacer increases water-solubility and decreases steric hindrance during ligation. TCO enable fast click chemistry under mild condition Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG4-acid is a click chemistry linker containing a TCO (trans-cycloctene) and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators such as EDC. , TCO reagent is highly reactive with tetrazine in an inverse electron demand Diels Alder (IEDDA) reaction followed by a retro-DA reaction. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG12-DBCO is a long chain PEGreagent containing a TCO and a DBCO moiety. TCO group specifically and efficiently reacts with terrahydrazine under mild condition. DBCO is very reactive toward Azide through click chemistry, the PEG spacer increases the aqueous solubility of the reagent. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG4-Acid is a stable tetrazines molecule containing a terminal carboxylic acid (CO2H) The terminal acid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. Methyltetrazine enable fast click chemistry with TCO ((trans-cycloctene), methyl group enhances the stability of tetrazine moiety. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-NHS Ester is a NHS actived building block containing a methyltetrazine group. It can react with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.