PEG

Methyltetrazine-Acid is a stable click chemistry building block. In the presence of activators (e.g. EDC, or HATU), it can be used to deriviate amine-containing molecule via a stable amide bond. Methyltetrazine enable fast click chemistry with TCO ((trans-cycloctene) under mild condition Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Tetrazine-Acid was found the fastest kinetics for bioorthogonal reaction with trans-cyclooctene (TCO) as the dienophile. The chemical stability of tetrazines is lower compared to methyltetrazines, but it is in acceptable range and thus can be applied for many applications. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-Amine possesses substantially improved stability compared to Tetrazine-Amine. It enable click chemistry with TCO (trans-cycloctene). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-Propylamine is click chemistry reagent, the amine group can be attached with carboxylic acid containing molecule in the presence of reagnet such as EDC or HATU. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene) Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG3-Maleimide is a click chemistry Maleimide linker. The maleimide group specifically and efficiently reacts with thiols to form thioether bond. This reagent can be used to efficieintly incorporate a tetrazine moiety with TCO-attached compound or macromolecule. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TAMRA-PEG4-Methyltetrazine is a fluorescent dye compound which can be labled to other macromolecule via click chemistry with TCO. Rhodamine is a commonly used red fluorescent dye tracer in biology for staining cells, tissues, biomarkers or nanoparticles. It has peak fluorescence emission at 572-575 nm. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG4-alkyne is a click chemistry bifunctional molecule containing an alkyne group and a hydrophilic PEG spacer which increases water-solubility. This reagent enables simple and efficient incorporation of a tetrazine moiety onto TCO-attached antibodies, peptide or other biomolecule The alkynes can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-DBCO is a TCO reactive reagent containing a methyltetrazine group and a DBCO moiety. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG3-azide is a herterobifunctional click chemistry reagent containing a methyltetrazine and azide moiety. The azide group can participate in copper-catalyzed Click Chemistry reactions with reagents such as alkynes, DBCO and BCN to form triazole moieties. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene) Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.