PEG

SIA Crosslinker is a non-cleavable, water-soluble crosslinker containig an NHS ester and an iodine group. The NHS ester is reactive toward amines while the iodine reacts with thiol groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

ANB-NOS Crosslinker contains a nitrophenyl azide group and an amine reactive NHS ester group. It is also able to react with nucleophiles. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSP Crosslinker is a cleavable crosslinker. It contains two terminal NHS ester moieties which can react with primary amines. The disulfide bonds can be cleaved via a reduction reaction using Dithiothreitol (DTT) reagent. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

EGS Crosslinker is a cleavable crosslinker which can be cleaved using hydroxyamine. EGS Crosslinkers contain two NHS ester groups which can react with primary amines. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Sulfo-NHS is used during the modificaiton of carboxylic groups to NHS ester groups. This can be used for crosslinking, labeling and other biological techniques. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

THP-SS-PEG1-t-butyl ester Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG1-SS-PEG1-t-butyl ester is a Click Chemistry crosslinker containing a propargyl group that can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The t-butyl protected carboxyl group prevents self coupling or polymerization under standard acid/amine or acid/hydroxyl coupling condition, t-butyl can be deprotected under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG1-SS-alcohol is a Click Chemistry-ready crosslinker containing a propargyl group, a hydroxyl group and a cleavable disulfide bond. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG1-SS-PEG1-acid is a Click Chemistry-ready crosslinker. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The propargyl groups is reactive with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.