PEG

Propargyl-PEG4-sulfonic acid is heterobifunction reagent that can reacts with azide compounds or biomolecules via copper catalyzed Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG8-bromide is a PEG reagent containing an alkyne group and a bromide group. The alkyne group can react with azide-bearing compounds or biomolecules in Click Chemistry reactions under the catalyzation of copper. The PEG spacer increases water-solubility of the molecule in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG6-amine is a crosslinker with a hydrophilic PEG spacer which can increase the hydrophilicity of the molecule in aqueous environment. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Bromo-PEG5-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Bis-PEG3-sulfonic acid is a PEG linker containing sulfonic acid moieties. Sulfonic acid can participate in esterification, halogenation and displacement reactions. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-Butoxycarbonyl-PEG4-sulfonic acid is a PEG linker containing a t-butyl protecting group and sulfonic acid moiety. t-bytl can be removed under acidic conditions. Sulfonic acid groups can participate in esterification, halogenation and replacement reactions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Carboxy-PEG2-sulfonic acid is a PEG linker containing a carboxylic acid and sulfonic acid end group. The terminal carboxylic acid can participate in reactions with primary amines in the presence of activators such as EDC and HATU. Sulfonic acid can undergo esterification, halogenation and replacement reactions. The hydrophilic PEG linker increases the compound's water solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-Butoxycarbonyl-PEG5-sulfonic acid is a PEG linker containing a t-butyl protecting group and a sulfonic acid moiety. t-butyl can be deprotected under acidic conditions. Sulfonic acid groups can participate in esterification, halogenation and replacement reactions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-Tos-N-(t-butoxycarbonyl)-aminoxy-PEG4-Tos is a PEG linker containing tosyl, boc and aminoxy moieties. Tosyl is a good leaving group and can also act as an alcohol protecting group in organic synthesis. The t-Boc protecting group can be removed under acidic conditions which allows for the amine group to be further reacted. The hydrophilic PEG linker increases the water solubility of the compound to further enhance the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.