PEG

Hydroxy-PEG3-sulfonic acid is a PEG linker containing hydroxyl and sulfonic acid. The hydroxyl group can participate in various reactions to further derivatize the compound. The sulfonic acid can undergo esterification, halogenation and displacement reactions. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Tetra(cyanoethoxymethyl) methane is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. The nitrile groups can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methylamino-PEG5-azide is a PEG linker containing an azide group and a methylamino group. The azide group enables Click Chemistry. The methylamine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

1,1,1-Trifluoroethyl-PEG5-Propargyl forms triazole linkage with azides via copper catalyzed azide-alkyne Click Chemistry. The trifluoroethyl group is reactive towards primary amine groups in proteins, antibody and other molecules and surfaces. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

1,1,1-Trifluoroethyl-PEG4-azide is a crosslinker containing an azide group and a trifluoroethyl group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. The trifluoroethyl group is used to react with lysine and other primary amine groups in proteins, antibody and other molecules and surfaces. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

PEG5-Ms is a PEG linker with a mesyl group and a hydroxyl group. The mesyl group is good leaving groups but can also be used as protecting groups for primary alcohols. They can be deprotected in the presence of sodium amalgam. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methylamino-PEG3-azide is a PEG linker containing an azide group with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Ms-PEG5-Ms are PEG linkers containing two mesyl moieties. The mesyl groups are good leaving groups and can also be used as protecting groups for primary alcohols. They can be deprotected in the presence of sodium amalgam. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG1-SS-PEG1-PFP ester is a Click Chemistry crosslinker. PFP ester is reactive with amine-bearing molecule. The propargyl groups can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.