Lipids

(14Z)-14-tricosenoic acid

Nervonic acid is a monounsaturated fatty acid important in the biosynthesis of myelin.

BP Lipid 374 is branched, multichargeable lipid which features a central PEG4 linkage to enhance biocompatibility. This lipid may be used in the development of lipid nanoparticles for drug delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG9-4-nitrophenyl carbonate serves as a PEG linker containing a nitrophenyl carbonate, which is readily displaced by amine nucleophiles to form carbamate bonds under mild conditions. The PEG9 chain bolsters the water solublity of the compound.

DSPE-PEG6-Mal is a PEG linker with a maleimide group, water-soluble PEG chain, a hydrophilic phosphate head with hydrophobic lipid tails. The polymer can self-assemble to form lipid bilayer in water. The phospholipid polyPEG can be used as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as liposomes in mRNA or DNA vaccines. The maleimide group will react with a thiol group to form a covalent bond.

Mal-PEG8-NH-Boc is a PEG linker possessing a terminal maleimide that will react with a thiol group to form a covalent bond and Boc protecting group that can be removed under acidic conditions to further react. The PEG8 chain enhances the water-solubility of the compound.

BP Lipid 379 is a multichargeable amino lipid analog of LP01. This lipid features a unique 2-hydroxyethyl piperazine head group four carbon atoms in length with an ester linkage to two asymmetric lipid tails comprised of a 15-carbon aliphatic tail and an adipate ester. This lipid may be used in the generation of lipid nanoparticles for drug delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 380 is an ionizable amino lipid analog which features a unique azetidine head group four carbon atoms in length with an ester linkage to two asymmetric lipid tails comprised of a branched aliphatic tail and an adipate ester. This lipid may be used in the generation of lipid nanoparticles for mRNA delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 381 is a branched amino lipid analog of LP01 which features a unique 3-hydroxy azetidine ionizable head group four carbon atoms in length with an ester linkage to two asymmetric lipid tails comprised of a 15-carbon aliphatic tail and an adipate ester. This lipid may be used in the formulation of lipid nanoparticles for mRNA delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.