Lipids

PI(3 5)P2 diC8 (Phosphatidylinositol 3 5-bisphosphate diC8) is a synthetic purified dioctanoyl PI(3 5)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 5-bisphosphate is in very low abundance and is required for retrograde membrane trafficking from lysosomal and late endosomal compartments to the Golgi and is involved in autophagy. PI(3 5)P2 levels are controlled by the 5-kinase PIKfyve and the 5-phosphatase Fig4/Sac3 and disregulation is linked to several human neuropathies (eg Chacot-Marie-Tooth disease).Product Keywords: Dioctanoyl Phosphatidylinositol 3 5-bisphosphate PtdIns(3 5)P2 (8:0/8:0) PI(3 5)P2 C8Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1. Marcus S. L. M. R. Wenk et al. (2001). "A synaptojanin-homologous region of Salmonella typhimurium SigD is essential for inositol pho

PI(3 5)P2 diC16 9Phosphatidylinositol 3 5-bisphosphate diC16) is a synthetic purified dipalmitoyl PI(3 5)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 5-bisphosphate is in very low abundance and is required for retrograde membrane trafficking from lysosomal and late endosomal compartments to the Golgi and is involved in autophagy. PI(3 5)P2 levels are controlled by the 5-kinase PIKfyve and the 5-phosphatase Fig4/Sac3 and disregulation is linked to several human neuropathies (eg Chacot-Marie-Tooth disease).Product Keywords: Dipalmitoyl Phosphatidylinositol 3 5-bisphosphate PtdIns(3 5)P2 (16:0/16:0) PI(3 5)P2 C16Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1. Ikonomov O. C. D. Sbrissa et al. (2002). "Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role

GroPI(3 4 5)P3 (Glycerophosphoinositol 3 4 5-triphosphate) is a synthetic phosphoinositide without acyl chains on the 1- & 2-positions of the glycerol.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2. Glycerophosphoinositol 3 4 5-triphosphate (GroPIP3) is missing the acyl chains from the 1- & 2-positions of the glycerol.

PI(3 4 5)P3 diC4 (Phosphatidylinositol 3 4 5-trisphosphate diC4) is a synthetic purified dibutanoyl PI(3 4 5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: Dibutanoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 (4:0/4:0) PI(3 4 5)P3 (4:0/4:0) or PIP3Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1. Thapar R. A. E. Karnoub et al. (2002). "Structural and biophysi

PI(3 4 5)P3 diC8 (Phosphatidylinositol 3 4 5-trisphosphate diC8) is a synthetic purified dioctanoyl PI(3 4 5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: Dioctanoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 (8:0/8:0) PI(3 4 5)P3 C8 or PIP3Bulk discounts available please email echelon@echelon-inc.com for information. Powered by Bioz See more details on Bioz

PI(3 4 5)P3 diC16 (Phosphatidylinositol 3 4 5-trisphosphate diC16) is a synthetic purified dipalmitoyl PI(3 4 5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: Dipalmitoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 C16 PI(3 4 5)P3 C16 or PIP3Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz1) Weiner O. D. P. O. Neilsen et al. (2002). "A PtdInsP(3)- and Rho GTPas

PI(3 4 5)P3 diC16 (Phosphatidylinositol 3 4 5-trisphosphate diC16) ammonium salt is a synthetic purified dipalmitoyl PI(3 4 5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: Dipalmitoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 C16 PI(3 4 5)P3 C16 or PIP3Bulk discounts available please email echelon@echelon-inc.com for information.

PI(3 4 5)P3 (D-myo-Phosphatidylinositol 3 4 5-trisphosphate) 17:0/16:0 is a synthetic PI(3 4 5)P3 analog with an unnatural C17 acyl chain at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2. Phosphatidylinositol 3 4 5-trisphosphate 17:0/16:0 is a synthetic PI(3 4 5)P3 analog with an unnatural C17 acyl chain at the sn-1 position. Product Keywords: Dipalmitoyl Phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 PI(3 4 5)P3 (17:0/16:0) or PIP3Bulk discounts a

PI(3 4 5)P3 (Phosphatidylinositol 3 4 5-trisphosphate) 18:0/20:4 is a synthetic purified PI(3 4 5)P3 with stearoyl and arachidonoyl acyl groups.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: 1-Stearoyl-2-arachidonoyl-phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 (18:0/20:4) PI(3 4 5)P3 (18:0/20:4) or PIP3Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz