Lipids

DBCO-PEG12-PFP ester consists of a DBCO which can be used for copper-free Click Chemistry reactions and PFP, which acts as a good leaving group that is readily displaced by amines to form amides. The PEG12 units improve the water solubility of the compound.

DSDMA is a fully saturated ionizable ether lipid featuring a dimethylamino head group and stearyl aliphatic tails. This compound may be used in the formulation of lipid nanoparticles (LNP's) for mRNA delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSPE-PEG-Hz-mal, MW 2,000 is a polyPEG compound with DSPE and maleimide groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic polyPEG increases the water solubility of the overall compound allowing for the delivery of the drug. Maleimide groups can react with thiol groups between pH 6.5 to 7.5.

An aliphatic amine featuring two oleyl fatty acid tails and a polar ethanolamine head group. This useful lipid scaffold may be further functionalized at the reactive free hydroxyl or used as a functional component for lipid nanoparticles. Reagent grade, for research purpose. Please contact us for GMP-grade.

An aliphatic amine featuring two saturated stearyl aliphatic tails and a polar ethanolamine head group. This useful lipid scaffold may be further functionalized at the reactive free hydroxyl or used as a functional component for solid lipid nanoparticles for drug delivery. Reagent grade, for research purpose. Please contact us for GMP-grade.

A multichargeable lipid featuring a bis-stearyl aliphatic amine tail group and a dimethylamine butanoate head group. This compound may be formulated into lipid nanoparticles for drug delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade.

BP Lipid 446 is a multichargeable lipid featuring three biodegrade amide tails, three amine spaces eight (8) carbon atoms long, and a central piperazine head group. This compound may be formulated into lipid nanoparticles for drug delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade.

PC Mal-PEG3-biotin functions as a photocleavable biotinylated reagent containing biotin, which has a strong binding with avidin or streptavidin for protein labeling or purification, and maleimide group, which will react with a thiol group. The PEG spacer imparts solubility in aqueous media. This structure allows for efficient photorelease of linked molecules, typically achieving over 90% cleavage in 5-25 minutes using a near-UV lamp.

3,3'-((2-hydroxyethyl)azanediyl)bis(N-(3-aminopropyl)propanamide)