Lipids

14-(Azide-PEG3-ethylcarbamoyl)tridecanoic-t-butyl ester has an azide group on a PEG linker with an alkane tail that has a t-butyl ester group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl group can be deprotected under acidic conditions. This compound may also be used as a building block for lipids in nanotechnolgy and drug delivery. Reagent grade, for research purpose.

20-(Bromoacetamido-PEG3-ethylcarbamoyl)nonadecanoic-t-butyl ester is a PEG linker with a bromine and an alkane tail that has a terminal t-butyl ester group. The bromine (Br) can be used as a leaving group for nucleophilic substitution reactions. The t-butyl group can be deprotected under acidic conditions. It may also be used to prepare more complex lipids for nanoparticles for drug delivery. Reagent grade, for research purpose.

14-(Amine-PEG5-ethylcarbamoyl)tridecanoic-t-butyl ester has an amine group on a PEG linker with an alkane tail that has a t-butyl ester group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The t-butyl group can be deprotected under acidic conditions. It is a self-assembling PEG reagent which may form micelles in water. This compound may also be used as a building block for lipids in nanotechnolgy and drug delivery. Reagent grade, for research purpose.

14-(Azide-PEG6-ethylcarbamoyl)tridecanoic-t-butyl ester is a PEG linker with an azide group and an alkane tail that has a terminal t-butyl ester group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl group can be deprotected under acidic conditions. The polymer can form micelles spontaneously in water. It may also be used to prepare more complex lipids for nanoparticles for drug delivery. Reagent grade, for research purpose.

20-(Bromoacetamido-PEG6-ethylcarbamoyl)nonadecanoic-t-butyl ester is a PEG linker with a bromine and an alkane tail that has a terminal t-butyl ester group. The bromine (Br) can be used as a leaving group for nucleophilic substitution reactions. The t-butyl group can be deprotected under acidic conditions. The polymer can form micelles spontaneously in water. It may also be used to prepare more complex lipids for nanoparticles for drug delivery. Reagent grade, for research purpose.

N4-Bz-5'-O-DMTr-2'-OMe-cytidine-3'-CED-phosphoramidite is a phosphoramidite monomer containing a 2'-OMe group and a cytosine nucleoside capped by a benzoyl functional group.

14-(Amine-PEG3-ethylcarbamoyl)tridecanoic t-butyl ester has an amine group on a PEG linker with an alkane tail that has a t-butyl ester group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The t-butyl group can be deprotected under acidic conditions. This compound may also be used as a building block for lipids in nanotechnolgy and drug delivery. Reagent grade, for research purpose.

Cbz-N-Amido-PEG10-Amido-tri-(carboxyethoxymethyl)-methane is an aqueous soluble PEG linker with a Cbz-protected amino group and three terminal carboxylic acids. The Cbz protecting group can be removed under catalytic hydrogenation conditions. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. HATU) to form stable amide bonds. Reagent grade, for research purpose.

N-(6-(2-hydroxyethylamino)hexyl)-2-hexyldecanamide has a terminal hydroxide group and two alkane tails split off of an amide group. This compound can be useful for the building or modification of lipid nanoparticles. Reagent grade, for research purpose.