Lipids

(6Z,16Z)-12-((Z)-dec-4-enyl)docosa-6,16-dien-11-yl 5-bromopentanoate is a lipid analogue of CL1 featuring a bromide head group and an ester linking to the branched polyunsaturated tail. This compound may be used to develop lipids for lipid nanoparticle-based drug delivery.

Azido-PEG-t-butyl ester, MW 2,000 is a polyPEG comprised of a 2k PEG polymer, azide group which can react with DBCO, BCN, alkyne via Click Chemistry to yield a stable triazole linkage, and a t-butyl ester group that can be deprotected under acidic conditions.

BP Lipid 377 is an ionizable amino lipid comprised of three linoleic acid tails and an N,N-dimethylamine head group four carbon atoms in length. This lipid may be used in the generation of lipid nanoparticles (LNPs) for mRNA and drug delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-PEG-t-butyl ester, MW 5,000 is a polyPEG reagent comprised of a 5k PEG polymer for enhanced hydrophilicity, azido group for click reactions with BCN, DBCO, alkyne, and t-butyl group that can be deprotected under acidic conditions.

BP Lipid 382 is a novel biodegradable lipid featuring one branched lipid tail, one adipic acid-based lipid chain, and a short four carbon chain functionalized with an ionizable 3-hydroxy azetidine head group. The head group is designed to provide dual polar and ionizable functionality. This compound may be used in the formulation of lipid nanoparticles (LNPs) for mRNA delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azide-PEG-Amide-PEG4-BDP FL, MW 2,000 is a fluorescent polyPEG compound comprised of a BDP FL dye moiety that is highly compatible with FAM fluorescence measuring instruments and a terminal azide that undergoes click reactions with BCN, DBCO, alkyne. The PEG polymer enhances the compound's aqueous solubility.

DBCO-N-bis(PEG4-amidoPEG8-TCO) is a branched PEG containing two TCO moeties which act as click chemistry handles that readily react with tetrazine groups on a target molecule. The DBCO group is a click chemistry handle which readily reacts with azide groups. The PEG8 spacer improves the water-solubility of the molecule.

Cy3-PEG-CH2CO2-NHS, MW 2,000 is reactive cyanine dye containing NHS group which enables labeling of amino-bearing biomolecules. The 2k PEG polymer enhances the hydrophilicity of the labeled entity. This reagent is ideal for the labeling of proteins, peptides, and oligonucleotides/DNA.

BP Lipid 407 is a PEG hybrid lipid featuring biodegradable ester linkages, two oleic acid tails and a PEG-linkage to a BOC-protected amine. The terminal group may be utlized for bioconjugation, surface modification, or as a novel component of lipid nanoparticles for delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.