Lipids

1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol (16:0 LysoPI LPI) is a synthetic purified palmitoyl PI.Lysophospholipids are lipid mediators which elicit a diverse array of cellular responses through activation of phospholipid specific G protein-coupled receptors. Lysophosphatidylinositol (LPI) induces a number of cellular effects through binding to the GPR55 receptor including angiogenesis bone morphogenesis cancer progression and pain. In addition LPI is thought to be a biomarker for certain cancers.

PI(3)P diC4 (Phosphatidylinositol 3-phosphate diC4) is a synthetic purified dibutanoyl PI(3)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4.Product Keywords: Dibutanoyl Phosphatidylinositol 3-phosphate PtdIns(3)P C4 PI(3)P C4 or PI3P C4Bulk discounts available please email echelon@echelon-inc.com for information.

PI(3)P diC8 (Phosphatidylinositol 3-phosphate diC8) is a synthetic purified dioctanoyl PI(3)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4.Product Keywords: Dioctanoyl Phosphatidylinositol 3-phosphate PtdIns(3)P C8 PI(3)P C8 or PI3P C8Bulk discounts available please email echelon@echelon-inc.com for information.

PI(3)P diC8 (Phosphatidylinositol 3-phosphate diC8) ammonium salt is a synthetic purified dioctanoyl PI(3)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4.Featured in Publications1) Mari M. E. Macia et al. (2001). "Role of the FYVE finger and the RUN domain for the subcellular localization of Rabip4." J Biol Chem 276(45): 42501-8.2) Kim S. A. G. S. Taylor et al. (2002). "Myotubularin and MTMR2 phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth disease." J Biol Chem 277(6): 4526-31.3) Koharudin L. M. W. Furey et al. (2009). "The phox domain of sorting nexin 5

PI(3)P diC16 (Phosphatidylinositol 3-phosphate diC16) is a synthetic purified dipalmitoyl PI(3)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4.Product Keywords: Dipalmitoyl Phosphatidylinositol 3-phosphate PtdIns(3)P C16 PI(3)P C16 or PI3PBulk discounts available please email echelon@echelon-inc.com for information.

PI(3 4)P2 diC4 (Phosphatidylinositol 3 4-bisphosphate diC4) is a synthetic purified dibutanoyl PI(3 4)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4-bisphosphate (PI(3 4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP TPTE etc.). PI(3 4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.Product Keywords: Dibutanoyl Phosphatidylinositol 3 4-bisphosphate PtdIns(3 4)P2 C4 PI(3 4)P2 C4 or PI34P2.Bulk discounts available please email echelon@echelon-inc.com for details.Publications Powered by Bioz See more details on Bioz1. Fernandes F. et al. (2011). "Phosphoinositides direct equine infectious anemia virus gag trafficking and release." Traffic 12(4): 438-451.2. Stampoulis P. T. Ueda et

PI(3 4)P2 diC8 (Phosphatidylinositol 3 4-bisphosphate diC8) is a synthetic purified dioctanoyl PI(3 4)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4-bisphosphate (PI(3 4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP TPTE etc.). PI(3 4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.Product Keywords: Dioctanoyl Phosphatidylinositol 3 4-bisphosphate PtdIns(3 4)P2 C8 PI(3 4)P2 C8 or PI34P2.Bulk discounts available please email echelon@echelon-inc.com for details.Publication Powered by Bioz See more details on Bioz1. Elge S. C. Brearley et al. (2001). "An Arabidopsis inositol phospholipid kinase strongly expressed in procambial cells: synthesis of PtdIns(4 5)P2 and PtdIns(3 4 5)P3

PI(3 4)P2 diC16 (Phosphatidylinositol 3 4-bisphosphate diC16) is a synthetic purified dipalmitoyl PI(3 4)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4-bisphosphate (PI(3 4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP TPTE etc.). PI(3 4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.Product Keywords: Dipalmitoyl Phosphatidylinositol 3 4-bisphosphate PtdIns(3 4)P2 (16:0/16:0) PI(3 4)P2 C16 or PI34P2.Bulk discounts available please email echelon@echelon-inc.com for details.Publication Powered by Bioz See more details on Bioz1. Dowler S. R. A. Currie et al. (1999). "DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides." Biochem J 342(Pt 1): 7-12.2. Karathanassis D.

PI(3 4)P2 diC16 (Phosphatidylinositol 3 4-bisphosphate diC16) ammonium salt is a synthetic dipalmitoyl PI(3 4)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4-bisphosphate (PI(3 4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP TPTE etc.). PI(3 4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.Solubility70:28:4 CHCl3:MeOH:H2O 0.5 mg/mlFeatured in Publications1) Dowler S. R. A. Currie et al. (1999). "DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides." Biochem J 342(Pt 1): 7-12.2) Karathanassis D. R. V. Stahelin et al. (2002). "Binding of the PX domain of p47(phox) to phosphatidylinositol 3 4- bisphosphate and phosphatidic acid is masked by an intramolecular interaction