Lipids

PI(3 4 5)P3 (Phosphatidylinositol 3 4 5-trisphosphate) 18:0/20:4 is a synthetic purified PI(3 4 5)P3 with stearoyl and arachidonoyl acyl groups.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3 4 5-trisphosphate (PIP3) formed from PI(4 5)P2 though phosphorylation by PI 3-kinase activates numerous signaling pathways resulting in cell proliferation growth survival glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4 5)P2 and SHIP to PI(3 4)P2.Product Keywords: 1-Stearoyl-2-arachidonoyl-phosphatidylinositol 3 4 5-trisphosphate PtdIns(3 4 5)P3 (18:0/20:4) PI(3 4 5)P3 (18:0/20:4) or PIP3Bulk discounts available please email echelon@echelon-inc.com for information.Publications Powered by Bioz See more details on Bioz

PtdIns(3 4 5)P3 3-methylenephosphonate diC8 (3C-PtdIns(3 4 5)P3 diC8) is a synthetic PI(3 4 5)P3 analog in which the 3-phosphate bond has been rendered metabolically stable as a methylenephosphonate. P-3C908 increases sodium transport across monolayers of cells A6 through activation of GLUT4. Powered by Bioz See more details on Bioz

PtdIns(3 4 5)P3 3-methylenephosphonate diC16 (3C-PtdIns(3 4 5)P3 diC16) is a synthetic PI(3 4 5)P3 analog in which the 3-phosphate bond has been rendered metabolically stable as a methylenephosphonate. P-3C916 increases sodium transport across monolayers of cells A6 through activation of GLUT4.

A synthetic phosphatidylinositol (3)-phospate [PI(3)P] analog in which the 3-phosphate has been rendered metabolically stable as a phosphothionate. P-3S18 has been shown to bind to the FYVE domain and is a substrate for the 5-kinase PIKfyve. Powered by Bioz See more details on Bioz

PtdIns(3 4 5)P3 3-phosphothioate diC8 (3S-PtdIns(3 4 5)P3 diC8) is a water-soluble synthetic PI(3 4 5)P3 analog in which the 3-phosphate has been rendered metabolically stable as a phosphorothioate. P-3S908 shows 90% inhibition of PTEN at 0.4µM. Powered by Bioz See more details on Bioz

PtdIns(3 4 5)P3 3-phosphothioate diC16 (3S-PtdIns(3 4 5)P3 diC16) is a synthetic PI(3 4 5)P3 analog in which the 3-phosphate has been rendered metabolically stable as a phosphorothioate. P-3S916 increases sodium transport across monolayers of cells A6 through activation of GLUT4.

Glycerophosphoinositol 4-phosphate (GroPI(4)P) is a synthetic purified PI(4)P without acyl chains at the 1- and 2-positions of the glycerol.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4 5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.Bulk discounts available please email echelon@echelon-inc.com for information.

Phosphatidylinositol 4-phosphate diC4 (PI(4)P diC4) is a synthetic purified dibutanoyl PI(4)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4 5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.Product Keywords: D-myo-Phosphatidylinositol 4-phosphate Dibutanoyl Phosphatidylinositol 4-phosphate PtdIns(4)P C4 PI(4)P C4 or PI4PBulk discounts available please email echelon@echelon-inc.com for information.

Phosphatidylinositol 4-phosphate diC8 (PI(4)P diC8) is a synthetic purified dioctanoyl PI(4)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4 5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.Alternate names: D-myo-Phosphatidylinositol 4-phosphate Dioctanoyl Phosphatidylinositol 4-phosphate PtdIns(4)P C8   PI(4)P C8 8:0/8:0 PI(4)PBulk discounts available please email echelon@echelon-inc.com for information.