Lipids

DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment. The phospholipid molecule consists of a hydrophilic phosphate connected to two hydrophobic saturated fatty acids by a glycerol molecule. In water, the molecule can orient itself into lipid bilayer and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSPE-succinic acid is a phospholipid compound with two 18-carbon lipid tails and a phosphate joined by a glycerol molecule. The molecule can self-assemble in water to form lipid bilayer with hydrophobic tails facing the inner area an d hydrophilic head facing outward interacting with water. The compound can be used to prepare nanoparticles or liposomes for drug nanocarrier to deliver therapeutics, such as mRNA/DNA vaccine. The carboxylic acid moiety is reactive with amine in the presence of activating agent, such as HATU or EDC, to from a stable amide linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DOPE-mPEG, MW 1,000 is a phospholipid polydisperse PEG which can self-assemble in an aqueous solution to form micelles/lipid bilayer. The amphiphilic polymer can be used to prepare liposome for targeted drug delivery application. Reagent grade, for research purpose.

DOPE-mPEG, MW 2,000 is an amphiphile PEG polymer which has unsaturated lipid tails. The polymer can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers. . Reagent grade, for research purpose.

DOPE-mPEG, MW 5,000 is a polymer which has both hydrophobic and hydrophilic moieties. The hydrophobic tails can be used to encapsulate therapeutic agents while the hydophobic PEG chain helps maintaining its water solubility. Reagent grade, for research purpose.

DOPE-PEG-Amine, MW 2,000 is an amphiphilic PEG polymer which can self-assemble in water to form micelles. The polymer can be used to prepare liposomes or nanoparticles for drug delivery applications. Amine moiety is reactive with NHS-ester to form an amide bond. Reagent grade, for research purpose.

DOPE-PEG-Amine, MW 3,400 is an active ester reactive phospholipid polyPEG. The polymer exhibits amphiphatic behavior and forms micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications. Reagent grade, for research purpose.

DOPE-PEG-Amine, MW 5,000 exhibits amphiphilic behavior in water by forming micelles. The polymer can be used to prepare liposome for drug carrier in targeted delivery applications. The amine terminal group can be reacted with an active NHS-ester to form a stable amide bond. Reagent grade, for research purpose.

DOPE-PEG-COOH, MW 1,000 is a carboxyl functionalized phospholipid PEG polymer. The amphiphilic polymer can form micelles in water and can be used to prepare liposomes for drug delivery application. The carboxyl group is reactive with amine in the presence of HATU or EDC to form a stable amide bond. Reagent grade, for research purpose.