Lipids

DOPE-PEG-COOH, MW 2,000 is an amphiphilic PEG polymer which can form micelles in water. The unsaturated lipid tails can be used to encapsulate hydrophobic drugs while maintaining water solubilty through the PEG chain. Carboxylic acid moiety is reactive with amine molecule in the presence of activating agents, such as HATU or EDC. Reagent grade, for research purpose.

DOPE-PEG-Mal, MW 2,000 is a phospholipid polyPEG which can form micelles in aqueous solution. The polymer can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond. Reagent grade, for research purpose.

DOPE-PEG-Mal, MW 3,400 has unsaturated lipids tails which can be used to encapsulate hydrophobic drugs while the PEG chain helps maintaining water solubulity. Maleimdie moiety is reactive with thio at pH 6.5 to 7.5 through thioether bond formation. Reagent grade, for research purpose.

DOPE-PEG-Mal, MW 5,000 is an amphiphilic polymer with unsaturated lipids and water soluble PEG chain. The lipid can be used to encapsulate lipophilic drugs or therapeutic agents such as in preparation of liposomes. The maleimide terminal group can be reacted with cysteine or other thiol molecule to form a stable thioether linkage. Reagent grade, for research purpose.

DSPE-PEG-Ald, MW 3,400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research purpose.

DSPE-PEG-Azide, MW 1,000 is a phospholipid with covalently attached polydisperse PEG. This polymer is commonly used for the preparation of long circulating liposomes. The azide moiety is reactive with alkyne to form a stable triazole bond. Reagent grade, for research purpose.

DSPE-PEG-Azide, MW 2,000 forms lipid bilayer/micelles spontaneously in water due to its amphiphilic structure. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The azide group enables click reaction with terminal alkyne via CuAAC or with cyclooctyne (such as DBCO or BCN) via SPAAC. Reagent grade, for research purpose.

DSPE-PEG-Azide, MW 3,400 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond. Reagent grade, for research purpose.

DSPE-PEG-Azide, MW 5,000 is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine. Reagent grade, for research purpose.