Lipids

2-undecyloxirane is a chemical reagent featuring an epoxy group on a C11 chain. The epoxy group undergoes ring opening in the presence of nucleophiles to form a branched structure containing a secondary alcohol. Compounds such as this may be used as intermediates in building lipids for use in lipid nanoparticles.

Oleic acid is a prevalent fatty acid that is found throughout nature in the form of triglycerides. Oleic acid is a monounsaturated C18 chain and features a carboxylic acid. Compounds such as this may be used as intermediates in building lipids for use in lipid nanoparticles.

DSPE-PEG-Maleimide, MW 3,400 is a PEG polymer functionalized with a DSPE phospholipid and maleimide group. The DSPE-PEG-Mal is a useful self-assembling reagent for PEGylated liposome or micelle while also providing an maleimide for coupling with thiol at pH 6.5-7.5. Reagent grade, for research purpose.

DSPC (1,2-distearoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine with saturated tails. It has a melting temperature of ~54°C and a cylindrical geometry that allows DSPC molecules to form a lamellar phase, which stabilizes the structure of lipid nanoparticles. DSPC has been used in the mRNA-1273 and BNT162b2 COVID-19 vaccines. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Pentacosadiynoic acid-MPEG, MW 1,000 is an amphiphilic polyPEG crosslinker. The polymer can self-assemble in aqueous solution to form micelles which then can be cross-linked under UV radiation (254 nm). The micelles can be used as nanoparticles for drug delivery application. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.