Lipids

BODIPY FL Phosphatidylinositol 4 5-bisphosphate is a water soluble analog of PI(4 5)P2 (PIP2) labeled with the green fluorophore Bodipy®-FL at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3 4 5)P3.Bulk discounts available please email echelon@echelon-inc.com for information. Powered by Bioz See more details on Bioz

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3 4 5)P3.GloPIPs are labeled at the sn-1 position with BODIPY®-FL (505/513) BODIPY®-TMR (544/574) or biotin. The sn-1 linkage in these labeled PIPs has been changed to a more stable amide from an ester. Results from experiments conducted at Echelon indicated that this minor chemical change did not have a significant effect in any of the applications tested.Bulk discounts available please email echelon@echelon-inc.com for information. Powered by Bioz See more details on Bioz

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3 4 5)P3.GloPIPs are labeled at the sn-1 position with BODIPY®-FL (505/513) BODIPY®-TMR (544/574) or biotin. The sn-1 linkage in these labeled PIPs has been changed to a more stable amide from an ester. Results from experiments conducted at Echelon indicated that this minor chemical change did not have a significant effect in any of the applications tested. Powered by Bioz See more details on BiozBulk discounts available please email echelon@echelon-inc.com for information.

BODIPY TMR PI(4 5)P2 (BODIPY TMR Phosphatidylinositol 4 5-bisphosphate) is a water soluble analog of PI(4 5)P2 (PIP2) labeled with the orange fluorophore Bodipy®-TMR at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3 4 5)P3.Bulk discounts available please email echelon@echelon-inc.com for information. Powered by Bioz See more details on Bioz

The Bodipy Labeled PIP Sample Pack contains 10ug of all eight Bodipy FL-labeled PIPs. These water soluble PI analogs are labeled with Bodipy®-FL at the sn-1 position.Sample pack contains:BODIPY® FL PhosphatidylinositolBODIPY® FL Phosphatidylinositol 3-PhosphateBODIPY® FL Phosphatidylinositol 4-PhosphateBODIPY® FL Phosphatidylinositol 5-PhosphateBODIPY® FL Phosphatidylinositol 3 4-BisphosphateBODIPY® FL Phosphatidylinositol 3 5-BisphosphateBODIPY® FL Phosphatidylinositol 4 5-BisphosphateBODIPY® FL Phosphatidylinositol 3 4 5-Trisphosphate

1 2-Dilauroyl-sn-glycerol is a diacylglycerol (DAG) involved in phospholipid metabolism and is a substrate of diacylglycerol kinase. 1 2-Diacylglycerols are formed in cells through the hydrolysis of phosphatidylinositol 4 5-bisphosphate by Phospholipase C. DAGs activate Protein Kinase C (PKC) which is a key regulator of signal transduction cellular regulation and tumor promotion. Powered by Bioz See more details on Bioz

1 2-Diacylglycerols (DAGs) are formed in cells through the hydrolysis of phosphatidylinositol 4 5-bisphosphate by Phospholipase C. DAGs activate Protein Kinase C (PKC) which is a key regulator of signal transduction cellular regulation and tumor promotion. Powered by Bioz See more details on Bioz

1 2-Diacylglycerols (DAGs) are formed in cells through the hydrolysis of phosphatidylinositol 4 5-bisphosphate by Phospholipase C. DAGs activate Protein Kinase C (PKC) which is a key regulator of signal transduction cellular regulation and tumor promotion. Powered by Bioz See more details on Bioz

1 2-Diacylglycerols (DAGs) are formed in cells through the hydrolysis of phosphatidylinositol 4 5-bisphosphate by Phospholipase C. DAGs activate Protein Kinase C (PKC) which is a key regulator of signal transduction cellular regulation and tumor promotion. Powered by Bioz See more details on Bioz