Lipids

BP Lipid 221 is an ionizable amino lipid which has both ester bonds located adjacent to C7 relative to the nitogen amine. This lipid is an analogous to BP-25498/ALC-0315. The head contains butanolamine which can efficiently encapsulate mRNA. The lipid can be used to prepare mRNA nanocarriers with good balance of delivery efficiency and pharmakokinetics as well as rapid lipid clearance profile. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 222 is an butanolamine ionizable lipid with both ester bonds located adjacent to C8 relative to the amine head. The introduction of ester linkages can improve the clearance of the lipid in the liver. This compound is analgous to ALC-0315 (BP-25498). The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 223 is an pentanolamine lipid with both ester bonds located adjacent to C6 relative to the amine head. The introduction of ester linkages can improve the clearance of the lipid in the liver. This compound is analgous to ALC-0315. The lipid can be used to prepare mRNA nanocarriers with good balance of delivery efficiency and pharmakokinetics as well as rapid lipid clearance profile. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 224 is an amino ionizable lipid analogous to BP-25498/ALC-0315. The pentanolamine lipid head enhances encapsulation of mRNA. The lipid has identical ester bonds located adjacent to C7 relative to the amine nitrogen. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 225 is an ionizable amine lipid with two identical ester tails adjacent to C8 position relative to amine. The head of lipid is pentanolamine which can effectively encapsulate mRNA used in gene therapies which depends on the availability of a safe and efficient delivery vehicle. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Octanoic acid is a saturated fatty acid with a terminal carboxylic acid. The carboxylic acid can react with primary amine groups in the presence of activators such as HATU.

Nonanoic acid is a saturated fatty acid with a terminal carboxylic acid. The carboxylic acid can react with primary amine groups in the presence of activators such as HATU.

Decanoic acid is a saturated fatty acid with a terminal carboxylic acid. The carboxylic acid can react with primary amine groups in the presence of activators such as HATU.

Undecanoic acid is a saturated fatty acid with a terminal carboxylic acid. The carboxylic acid can react with primary amine groups in the presence of activators such as HATU.