Lipids

H-Gly-Gly-Gly-OH is a tripeptide featuring three glycine residues. Both its C- and N-termini are deprotected and may be used to react with a variety of chemical structures to form larger compounds.

C12-200 is an ionizable lipid used to generate lipid nanoparticles (LNPs) for delivery of siRNA mRNA and saRNA in several cell types and animal models. C12-200 LNPs were able to safely deliver placental growth factor mRNA to the placenta in a pregnant mouse model.

DSPE-PEG-Maleimide, MW 1,000

Heptyl 7-bromoheptanoate can be useful for the preparation of lipid nanoparticles. Reagent grade, for research use only.

BP Lipid 227 is an ionizable lipid. The ethanolamine amino lipid head enhances encapsulation of mRNA. The lipid has primary esters at C5 position relative to the amine nitrogen. The primary lipid tail has an 8 carbon tail. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 228 is an ionizable lipid. The dimethylamine lipid head enhances encapsulation of mRNA. The lipid has a C5 amide connection and two primary esters at C8 position relative to the amide nitrogen. The primary lipid tail has a mixture of 4 and 6 carbon tails. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle. The pKa is 6.5. Reagent grade, for research use only.

DOPE-PEG-Azide, MW 1,000 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring. Reagent grade, for research use only.

DOPE-PEG-Azide, MW 2,000 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring. Reagent grade, for research use only.

DOPE-PEG-Azide, MW 3,400 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring. Reagent grade, for research use only.