Lipids

1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanol (PLPEth) is a form of phosphatidylethanol (PEth) which is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phospholipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes and is one of the longest-lived circulating EtOH metabolite yet identified. PLPEth is a one of five most abundant naturally occurring PEth species.

1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanol (SLPEth) is a form of phosphatidylethanol (PEth) which is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phosphlipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes and is one of the longest-lived circulating EtOH metabolite yet identified. SLPEth is a one of five most abundant naturally ocurring PEth species.

The Pure Liposome is prepared form asolectin through homogenizing the asolectin suspension with an ultrasonic homogenizer. And it is raw material for proteoliposome proteins production by <i>in vitro<i> wheat germ expression system.

ALC-0315 is an ionizable lipid which has been used to form lipid nanoparticles for delivery of RNA. ALC-0315 is one of the components in the BNT162b2 vaccine against SARS-CoV-2 in addition to ALC-0159 DSPC and cholesterol. This is a reagent grade product for research use only.

C13-112-tetra-tail is an ionizable lipid molecule containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

C13-112-tri-tail is an ionizable lipid molecule containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

C13-113-tetra tail is an ionizable lipid molecule containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

C13-113-tri tail is an ionizable lipid molecule containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG8-DSPE is a PEG linker containing DSPE and methoxy moieties. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.