Lipids

OH-Chol is a cationic cholesterol derivative that can be used as a component of lipoplexes complexes. Reagent grade, for research use only.

Cholesteryl Oleate is a cholesterol ester. The liver is a primary source of cholesteryl oleate, esterified form cholesterol, that enriches the LDL particles when released into plasma. Cholesteryl Oleate has been used in the generation of nanoparticles and liposomes for drug delivery. Reagent grade, for research use only.

HAPC-Chol is a cationic cholesterol that can be used as a component of lipoplexes complexes. Reagent grade, for research use only.

MHAPC-Chol is a cationic cholesterol that can be used as a component of lipoplexes complexes. Reagent grade, for research use only.

DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol can bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA. Reagent grade, for research use only.

DMHAPC-Chol is a cationic cholesterol. Liposomes incorporating DMHAPC-chol have been employed for the in vitro and in vivo delivery of DNA plasmids. Reagent grade, for research use only.

Cholesteryl Myristate is a fatty acid that is found in the outer membrane of cells. It has been shown to be an effective cationic surfactant and to form films at low concentrations. Reagent grade, for research use only.

Dios-Arg (trifluoroacetate salt) is a steroid-based cationic lipid that contains a diosgenin skeleton coupled to an L-arginine head group. Dios-Arg forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratio greater than or equal to 4. Reagent grade, for research use only.

2H-Cho-Arg (trifluoroacetate salt) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. 2H-Cho-Arg forms a complex with plasmid DNA (pDNA) and decreases pDNA migration in an electrophoretic mobility shift assay at +/- charge ratios of 4 or higher. Reagent grade, for research use only.