Lipids

Cho-Arg (trifluoroacetate salt) is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. Cho-Arg forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Reagent grade, for research use only.

Cholesteryl Hemisuccinate is an oxidation product of polyunsaturated fatty acid of cholesterol that alters lysosome structure and functions and induces proinflammatory cytokine production in macrophages. Reagent grade, for research use only.

Omega-azido-C6 Ceramide is a clickable form of C6 ceramide. Omega-azido-C6 Ceramide can also be used to conjugate alkynylated fluorescent probes. Reagent grade, for research use only.

Sphingosine-1-phosphate (d17:1) is a synthetic sphingolipid that has been used as an internal standard for the quantification of sphingosine-1-phosphate (d18:1). Reagent grade, for research use only.

Sphingosine-1-phosphate (d16:1) is a derivative of sphingosine-1-phosphate. Sphingosine-1-phosphate (d16:1) is an important regulator of a wide variety of biological processes acting as an endogenous ligand to EDG/S1P receptors. Reagent grade, for research use only.

D-erythro Lysosphingomyelin (d18:1) is a sphingolipid that is found in the cytosolic and plasma membranes of cells. It is involved in cell signaling, with various biological effects on cells. Lysosphingomyelin has been shown to be reactive with free radicals, leading to cytotoxic effects on cells. Reagent grade, for research use only.

C16 Sphingomyelin (d18:1/16:0) is a sphingomyelin with palmitic acid inserted at the acylation position. Sphingomyelin is a type of sphingolipid found in animal cell membranes. Reagent grade, for research use only.

Sphingosine-1-phosphate (d18:1) is the product of phosphorylation of sphingosine by sphingosine kinase that is secreted from cells and acts as an agonist at S1P receptors. Reagent grade, for research use only.

mPEG-Cholesterol, MW 2,000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles. Reagent grade, for research use only.