Cell Line

Please note that an MTA needs to be signed prior to purchase of this product, we kindly request that you contact your local office. This product is provided at this price to private organisations.

. Gender: Caucasian. Ethnicity: Epithelial Please note this product may be subject to fees, we invite you to contact your local office.

Motor Neurons from ALS iPSCs. Express HB9, ISL1, ChAT. Functional with spontaneous activity. Ideal for ALS research.

Motor Neurons from ALS iPSCs. Express HB9, ISL1, ChAT. Functional with spontaneous activity. Ideal for ALS research.

Motor Neurons with TDP-43 Q331K mutation (HET). Useful for ALS and neurodegenerative disease studies.

Motor Neurons with TDP-43 Q331K mutation (HET). Useful for ALS and neurodegenerative disease studies.

Human Motor Neurons (iPSC-derived, TDP43 mutation, Q331K, HOM)

Human Motor Neurons (iPSC-derived, TDP43 mutation, Q331K, HOM)

Please note this product may be subject to fees, we invite you to contact your local office. ADAR1 Responsive Luciferase Reporter HEK293 Cell Line is a HEK293 cell line designed to respond to ADAR1 enzymatic activity. These cells were engineered to express an ADAR1 reporter construct comprised of an ADAR1 hairpin target with a stop codon (UAG) susceptible to ADAR1-mediated editing to tryptophan (UUG), located upstream of a firefly luciferase reporter. This cell line has been validated by comparing reporter activation after transfection with ADAR1 and ADAR2. This cell line has been used for the development of the constitutive ADAR1 expressing ADAR1 Activity Luciferase Reporter HEK293 Cell Line (#82239). The ADAR1 reporter construct is compromised of an ADAR1 hairpin targer with a stop codon (UAG) upstream of the sequence encoding luciferase. In the presence of ADAR1 activity, as in the case of transfection with ADAR1, adenine is converted into inosine encoding now the amino acid tryptop