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Click Chemistry

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    Results for Click Chemistry ( 905 )

      • Boc-PEG4-Val-Ala-PAB

        Ref: BP-28019
        Sizes: 100 MG, 50 MG, 500 MG, 250 MG
        From: €525.00

        Boc-PEG4-Val-Ala-PAB is a cleavable PEG ADC linker. The Val-Ala peptide will specifically be cleaved by Cathepsin B. Boc group can be removed under acidic condition. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

        Product detail

      • Boc-PEG4-Val-Ala-PAB-PNP

        Ref: BP-28020
        Sizes: 100 MG, 50 MG, 500 MG, 250 MG
        From: €975.00

        Boc-PEG4-Val-Ala-PAB-PNP is an ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, a Val-Ala dipeptide, a PAB group, and a PNP carbonate. The PNP carbonate is a leaving group that is highly activated towards attack from amines to form carbamates with the target molecule, while the Boc protecting group may be removed with acid to reveal a primary amine which can be used to couple with carboxylic acids. The Val-Ala dipeptide is cleaved by proteases to release a given drug payload via an elimination mechanism within the PAB group.

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      • Fmoc-PEG4-Val-Ala-PAB

        Ref: BP-28021
        Sizes: 100 MG, 50 MG, 500 MG, 250 MG
        From: €525.00

        Fmoc-PEG4-Val-Ala-PAB is a cleavable PEG ADC linker with an Fmoc-protected amine. The Val-Ala peptide will specifically be cleaved by Cathepsin B. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

        Product detail

      • Fmoc-PEG4-Val-Ala-PAB-PNP

        Ref: BP-28022
        Sizes: 100 MG, 50 MG, 500 MG, 250 MG
        From: €975.00

        Fmoc-PEG4-Val-Ala-PAB-PNP is a cleavable PEG ADC linker with an Fmoc-protected amine. The Val-Ala peptide will specifically be cleaved by Cathepsin B. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. PNP is a good leaving group. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

        Product detail

      • Azido-PEG4-Val-Ala-PAB

        Ref: BP-28023
        Sizes: 100 MG, 50 MG, 500 MG, 250 MG
        From: €525.00

        Azido-PEG4-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. Azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry. PEG space improve compound's aqueous solubility. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

        Product detail

      • Azido-PEG4-Val-Ala-PAB-PNP

        Ref: BP-28024
        Sizes: 100 MG, 50 MG, 500 MG, 250 MG
        From: €975.00

        Azido-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. Azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry. PEG space improve compound's aqueous solubility. PNP is a good leaving group. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

        Product detail

      • Mal-PEG4-Val-Ala-PAB

        Ref: BP-28025
        Sizes: 100 MG, 50 MG, 500 MG, 250 MG
        From: €525.00

        Mal-PEG4-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. Maleimide (Mal) group is reactive toward thiol groups. PEG space improve compound's aqueous solubility. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

        Product detail

      • Mal-PEG4-Val-Ala-PAB-PNP

        Ref: BP-28026
        Sizes: 100 MG, 50 MG, 500 MG, 250 MG
        From: €975.00

        Mal-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. Maleimide (Mal) group is reactive toward thiol groups. PEG space improve compound's aqueous solubility. PNP is a good leaving group. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

        Product detail

      • Mal-Val-Ala-PAB

        Ref: BP-28054
        Sizes: 100 MG, 50 MG, 500 MG, 250 MG
        From: €525.00

        Mal-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. Maleimide (Mal) group is reactive toward thiol groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

        Product detail