Click Chemistry

MB 543 DBCO is a fluroescent agent with a terminal DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. MB 543 Alkyne is very hydrophilic, water-soluble orange fluorescent dye that has a maximal absorption of 543 nm and emission at 566 nm. The compound is also pH insensitivity from pH 3 to pH 10. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

UBQ-3 DBCO is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal DBCO group. UBQ-3 DBCO has a wide and intense quenching range from 620-730 nm makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

IR 650 Azide is a fluroescent agent with a terminal azide group. IR 650 Azide very hydrophilic, water-soluble far-red fluorescent dye that has a maximal absorption of 651 nm and emission at 668 nm. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage and as an azide-copper complex, the reaction works well under diluted conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

IR 650 Alkyne is a fluroescent agent with a terminal propargyl group. The alkyne in this linker can react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reaction. IR 650 Alkyne very hydrophilic, water-soluble far-red fluorescent dye that has a maximal absorption of 651 nm and emission at 668 nm. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

IR 650 DBCO is a fluroescent molecule with a terminal propargyl group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. IR 650 DBCO very hydrophilic, water-soluble far-red fluorescent dye that has a maximal absorption of 651 nm and emission at 668 nm. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

IR 750 Alkyne is a fluroescent molecule with a terminal propargyl group. The propargyl moiety in this linker can react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reaction. IR 750 Alkyne is a near-red, water-soluble dye that is structurally similar to other 750 dyes which absorbs at 756 nm and emits at 776 nm. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

IR 750 DBCO is a fluroescent molecule with a terminal DBCO group. IR 750 DBCO is a near-red, water-soluble dye that is structurally similar to other 750 dyes which absorbs at 756 nm and emits at 776 nm. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-PEG4-MMAE is a synthetic antineoplastic agent coupled to an azide group by a PEG linker. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells. Mal is reactive with thiol group of antibody. The azide group can react with alkyne, BCN, DBCO via Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Amino-PEG4-MMAE is a PEG linker consisting of an MMAE warhead linked to a primary amine. The amine group can be linked to a number of different structures such as carboxylic acids, NHS esters, aldehydes, ketones, Michael acceptors, and heterocycles. The MMAE warhead is a toxin that is delivered to cells to cause apoptosis.