Lab Tools

NOCs are stable NO-amine complexes that spontaneously release NO, without cofactors, under physiological conditions. The rate of NO release depends on the chemical structure of NOC. The mechanism of spontaneous NO generation by NOCs is very simple compared to other classical NO donors, such as nitroglycerin and nitropurusside, and the by-products do not interfere with cell activities. 

NOCs are stable NO-amine complexes that spontaneously release NO, without cofactors, under physiological conditions. The rate of NO release depends on the chemical structure of NOC. The mechanism of spontaneous NO generation by NOCs is very simple compared to other classical NO donors, such as nitroglycerin and nitropurusside, and the by-products do not interfere with cell activities. 

NORs are ideal NO donors with completely different chemical structures from the other NO donors. Although NORs do not have any ONO2 or ONO moiety, they spontaneously release NO at a steady rate. Even though the NO release mechanism of NOR has not been completely determined, it is confirmed that the byproducts do not possess any significant bioactivities. NOR 3, isolated from Streptomyces genseosporeus, is reported to have strong vasodilatory effects on rat and rabbit aortas and dog coronary arteries.

Application: Spontaneous NO donor, nitrosothiol compound

Application: Spontaneous NO donor, nitrosothiol compound

- Simple preparation of NTA-SAM on gold surface - Efficient Immobilization of histidine-tagged proteins - Suppress unspecific binding with unknown proteins

n-Octyl-β-D-glucoside has definite advantages over the conventional non-ionic detergents as a membrane protein solubilizer. It can be easily separated by dialysis and has very little interaction with membrane proteins. Its CMC value is 25 mM. It is strongly recommended for studies of ATPase or NADH dehydrogenase.

n-Octyl-β-D-glucoside has definite advantages over the conventional non-ionic detergents as a membrane protein solubilizer. It can be easily separated by dialysis and has very little interaction with membrane proteins. Its CMC value is 25 mM. It is strongly recommended for studies of ATPase or NADH dehydrogenase.

n-Octyl-β-D-thioglucoside is similar to n-Octyl-β-D-glucoside. After solubilization, it can be separated from phospholipid or protein by dialysis. It does not interfere with enzyme activities. It is more stable than n-Octyl-β-D-glucoside and is not affected by esterase. Its CMC value is 9 mM.