PEG

[2-(Fmoc-amino)acetamido]Acetate-Cbz is a cleavable ADC linker with an Fmoc group and a benzyl (Cbz) protecting group. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The benzyl protecting group can be removed via hydrogenolysis to form a free amine. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

[2-(Fmoc-amino)acetamido]-acid is a cleavable ADC linker with an Fmoc group and a terminal carboxylic acid group. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5-Ethynyl-2'-deoxyuridine (EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferations. The alkyne handler can be used for subsequent ligation to azide-containing molecules through a highly efficient click chemistry reaction. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Calaspargase pegol is used to treat acute lymphoblastic leukemia.

PEG-9 Laurate is a bioactive chemical.

Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus a short amide-PEG linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus a short amide-PEG linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-PEG4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-PEG5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.