PEG

3,4-Dibromo-Mal-PEG8-Azide is a PEG linker featuring a dibromo-maleimide linked to an azide group. The unsaturated dibromo motif is a covalent ligand for thiol groups, and may be used to label cysteine residues in proteins. The azide is a click chemistry handle which may be used to link with terminal alkynes or strained cyclooctynes like DBCO or BCN. The presence of two leaving groups on this molecule allows this linker to bind two thiols at a time.

N-Mal-N-bis(PEG8-NHS ester) is a trifunctional linker with two NHS esters and a maleimide function. The NHS esters are activated towards attack from a nucleophile such as amines or alcohols while the maleimide serves as a covalent ligand to strongly bind thiols such as those found in the amino acid, cysteine.

N-bis(Amine-PEG8)-N-(PEG8-acid), HCl salt is a 3-arm PEG linker consisting of a carboxylic acid group with two amino groups. The amino (NH2) groups are reactive with activated NHS esters or carboxylic acid. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond. Reagent grade, for research purpose.

Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG arm increases solubility in aqueous media. Reagent grade, for research use only.

TCO-PEG4-maleimide is a click chemistry building block containing a TCO moiety and a maleimide group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. TCO moiety is very reactive with tetrazine (3rd generation click chemistry). Reagent grade, for research purpose.

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N-(Biotin-PEG10)-N-Bis(PEG10-azide) is a branched PEG linker with two biotin groups. The azide groups enables click chemistry. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azide-PEG11-Ms is a very reactive reagent containing an azide group and a mesyl group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The mesyl group is good leaving group for nucleophilic reaction. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(Amine-PEG3)-N-bis-(PEG3-Amino-Tri-(Propargyl-PEG2-ethoxymethyl)-methane), TFA salt is a branched PEGylation reagent containing an amino group with six propargyl groups. The amino group is reactive with carboxylic acids, activated NHS esters. The alkyne can participate in copper-catalyzed Click Chemistry. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.