PEG

Hydroxy-PEG4-CH2CO2H is a PEG linker containing a hydroxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG4-Ms has an alkyne group and a mesylate group. The mesylate group is a sulfonate ester for nucleophilic substitution reaction (SN2). The alkyne group can react with azides via copper catalyzed Click Chemistry reactions. The PEG units help increase the solubility of the molecule in aqueous environment. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-PEG3-flouride is a PEG linker containing a fluoride group and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSPE-PEG-CY5.5, MW 2,000 is a water-soluble dye coupled to a PEG polymer with hydrophilic phosphate head and hydrophobic lipid tails. Absorbance and emission of the dye are identical to Cy5.5 fluorophore. The polymer can self-assemble to form lipid bilayer in water. The phospholipid polyPEG can be used as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as liposome in mRNA or DNA vaccines. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-PEG8-(CH2)3-aldehyde is a monodisperse PEG crosslinker containing an azide group and an aldehyde group. The azide group enables PEGylation via Click Chemistry. PEG8 spacer increases solubility in aqueous media. The aldehyde group can be used in PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Hydroxy-PEG1-acid sodium salt is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Propargyl-PEG12-methylamine is a propargyl linker that is commonly used as a Click Chemistry reagent for copper-catalyzed reactions with azides. The methylamine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The PEG spacer helps improve the water solubility of the molecule in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(amine-PEG23)-N-bis(PEG3-azide) is a PEG reagent containing a terminal amine and two azide groups. The hydrophilic PEG spacer increases solubility in aqueous media. The azide groups can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Diphenylthiol-Mal-PEG8-PEG4-Biotin is a biotinylation reagent with a diphenylthiol-maleimide group, which has been shown to have antibacterial properties. PEG attached to the biotin gives an extended spacer arm that permits the biotin to reach into the binding pocket of the protein or macromolecule. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.