PEG

Cbz-N-Amido-PEG10-Amido-tri-(carboxyethoxymethyl)-methane is a aqueous soluble PEG linker with a Cbz-protected amino group with three terminal carboxylic acids. The Cbz protecting group can be removed under acidic conditions. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose.

18-(Bromoacetamido-PEG4-ethylcarbamoyl)heptadecanoic-t-butyl ester has a bromide group on a PEG linker with a alkane tail that has a t-butyl ester group. The bromide (Br)can be used as a leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions. 18-(Bromoacetamido-PEG4-ethylcarbamoyl)heptadecanoic-t-butyl ester is a self-assembling PEG reagent which may form micelles in water. This compound may also be used as a building block for lipids in nanotechnolgy and drug delivery. Reagent grade, for research purpose.

14-(Amine-PEG6-ethylcarbamoyl)tridecanoic-t-butyl ester is a PEG linker with an amine group and an alkane tail that has a terminal t-butyl ester group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The polymer can form micelles spontaneously in water. It may also be used to prepare more complex lipids for nanoparticles for drug delivery. Reagent grade, for research purpose.

Azido-PEG23-azide is a aqueous soluble, homebifunctional PEG reagent The azide (N3) group cis very reactive with alkyne, such as BCN, DBCO via Click Chemistry to yield a stable triazole moiety Reagent grade, for research purpose.

DSPE-PEG-Fluor 488, MW 2,000 is a powerful labeling dye and PEG polymer with hydrophilic phosphate head and hydrophobic lipid tails. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The polymer can self-assemble to form lipid bilayer in water. The phospholipid polyPEG can be used as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as liposome in mRNA or DNA vaccines. BP Fluor 488 is a pure 5- sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences. Reagent grade, for research purpose.

DSPE-PEG-Fluor 647, MW 2,000 is a bright green-fluorescent dye and PEG polymer with hydrophilic phosphate head and hydrophobic lipid tails. The dye is water soluble and pH-insensitive from pH 4 to pH 10. The dye has 4 sulfonate groups make it high water soluble and less aggregation in the aqueous solution. The polymer can self-assemble to form lipid bilayer in water. Reagent grade, for research purpose.

Biotin-PEG10-Acid is a biotin PEG linker containing a carboxylic acid group, it is reactive with amine moiety. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. Reagent grade, for research purpose.

14-(Bromoacetamido-PEG3-ethylcarbamoyl)tridecanoic t-butyl ester has a bromide group on a PEG linker with a alkane tail that has a t-butyl ester group. The bromide (Br)can be used as a leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions. 14-(Bromoacetamido-PEG3-ethylcarbamoyl)tridecanoic t-butyl ester is a self-assembling PEG reagent which may form micelles in water. This compound may also be used as a building block for lipids in nanotechnolgy and drug delivery. Reagent grade, for research purpose.

18-(Bromoacetamido-PEG5-ethylcarbamoyl)heptadecanoic-t-butyl ester has a bromide group on a PEG linker with a alkane tail that has a t-butyl ester group. The bromide (Br)can be used as a leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions. 18-(Bromoacetamido-PEG5-ethylcarbamoyl)heptadecanoic-t-butyl ester is a self-assembling PEG reagent which may form micelles in water. This compound may also be used as a building block for lipids in nanotechnolgy and drug delivery. Reagent grade, for research purpose.