PEG

2,3-(PEG4-Azide)-1-(PEG4-N-Boc)methane is a trifunctional PEG compound containing two azides and a Boc-protected primary amine. Azides are highly reactive towards terminal alkynes and strained cyclooctynes such as DBCO and BCN, while the amine may be deprotected under acidic conditions to allow for nucleophilic activity, such as in forming amides from carboxylic acids.

0

0

Thalidomide-O-amido-C3-PEG3-C1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

0

0

0

0

0