PEG

FmocNH-PEG4-t-butyl ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the selective degradation of proteins through the ubiquitin-proteasome system within cells.

Pomalidomide 4'-PEG3-azide is a chemically synthesized E3 ligase ligand-linker conjugate that incorporates the cereblon ligand derived from Pomalidomide, along with a linker. This compound is utilized in the synthesis of iRucaparib-TP3 (Compound 3), an effective PARP1 degrader developed through the PROTAC strategy and derived from Rucaparib.

Pomalidomide-amino-PEG3-NH2 hydrochloride is an E3 ligase ligand-linker conjugate containing a pomalidomide-based cereblon ligand and a linker, which can be used to synthesize PROTACs.

Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized chemical compound that functions as an E3 ligase ligand-linker conjugate, combining a Pomalidomide-based cereblon ligand with a linker commonly used in PROTAC technology.

Azido-PEG2-C6-Cl, a PEG-based linker for PROTACs, joins two essential ligands for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG6-MS, a PEG-based linker for PROTACs, connects two essential ligands necessary for forming PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Bis-PEG6-t-butyl ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ethyl-PEG4-alcohol is a PEG-based linker for PROTACs, facilitating the coupling of two essential ligands necessary for PROTAC molecule formation and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Hydroxy-PEG4-methyl acetate, a PEG-based linker compound, is utilized in PROTAC synthesis.