Nucleotides

Triphosphopyridine nucleotide is a coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. Triphosphopyridine nucleotide serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Uridine-5'-triphosphoric acid trisodium salt, also known as UTP, is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Uridine 5'-monophosphateis a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. It is also used in foods such as infant formula to as a method of increasing uridine levels in blood. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Mizoribine is an imidazole nucleoside immunosuppressant agent that was first isolated from the mold Eupenicillium brefeldimium with antibiotic and cytotoxic effects. Mizoribine has been used in kidney transplantation, which is the optimal form of therapy for children and adolescents with end-stage kidney disease. The compound has also been used to treat steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases. Mizoribine's mode of action is via selective inhibition of inosine monophosphate synthetase and guanosine monophosphate synthetase, resulting in the complete inhibition of guanine nucleotide synthesis without incorporation into nucleotides. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Udp-alpha-d-n-acetylgalactosamine, disodium salt is a donor substrate for N-acetylgalactosaminyltransferases. Udp-alpha-d-n-acetylgalactosamine, disodium salt is useful in the synthesis of aryl azide derivatives that can be employed in affinity labeling of glycosyltransferases and UDP-HexNAc pyrophosphorylase. Udp-alpha-d-n-acetylgalactosamine, disodium salt can be used to treat and prevent renal inflammation association with infection. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. 2'-Deoxy-2'-fluorouridine has been shown to inhibit the replication of resistant mutants in vitro, and this inhibition can be reversed by increasing the concentration of 2'-deoxy-2'-fluorouridine. 2'-Deoxy-2'-fluorouridine also binds to duplexes of dsDNA with high affinity and specificity. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine / PSI-6206 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) RNA polymerase. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5-Fluorouridine is a modified uridine nucleoside with a fluorine atom at position 5 of the uracil. 5-Fluorouridine is a highly cytotoxic metabolite of 5-fluorouracil, a drug used to treat a variety of cancers, on the market with the trade name Adrucil. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.