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- From: €1,027.00
Screen for 3CL protease inhibitors in a BSL-1 environment. This is an extremely bright and robust 3CLpro assay, packaged in BacMam for mammalian cell expression. Green fluorescence increases when 3CLpro is successfully inhibited. Kit comes with the 3CLglowUp biosensor BacMam, 3CLPro enzyme BacMam, and 500mM Sodium butyrate in H2O.
- From: €1,027.00
The 3CLglowLive Assay kit is well suited to experiments using the live SARS-CoV-2 virus. It is dim at baseline but fluoresces green in the presence of 3CL protease activity, an indicator of SARS-CoV-2 viral replication. The kit includes 2 BacMam viruses - one expressing the 3CLglowLive biosensor and the other a 3CLpro enzyme, which could be used to test the biosensor and optimize fluorescence detection settings.