Cell-based Assays

Please note this product may be subject to fees, we invite you to contact your local office.Nectin-4 Knockout MCF7 Cell Line is an MCF7 breast cancer cell line in which human Nectin-4 has been genetically removed using CRISPR/Cas9 genome editing with a lentivirus encoding CRISPR/Cas9 gene and sgRNA (single guide RNA) targeting human Nectin-4. This cell line has been validated by genomic sequencing and flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office.TROP2 Knockout MCF7 Cell Line is an MCF7 breast cancer cell line in which human TROP2 (Trophoblast cell-surface antigen 2 or TACSTD2) has been genetically removed using CRISPR/Cas9 genome editing with a lentivirus encoding CRISPR/Cas9 gene and sgRNA (single guide RNA) targeting human TROP2. This cell line has been validated by genomic sequencing and flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office.EGFR Knockout A549 Cell Line is an A549 lung cancer cell line in which human EGFR (epidermal growth factor receptor) has been genetically removed using CRISPR/Cas9 genome editing with a lentivirus encoding CRISPR/Cas9 gene and sgRNA (single guide RNA) targeting human EGFR. This cell line has been validated by genomic sequencing and flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office.Firefly Luciferase BCMA Knockout RPMI-8226 Cell Line is a RPMI-8226 cell Line constitutively expressing firefly (Photinus pyralis) luciferase under the control of a CMV promoter, and in which BCMA (B-Cell Maturation Antigen, or CD269) has been genetically removed using CRISPR/Cas9 genome editing. This cell line was generated by using Firefly Luciferase Lentivirus (BPS Bioscience #79692). This cell line has been validated by genome sequencing, flow cytometry and luciferase activity measurement.

Please note this product may be subject to fees, we invite you to contact your local office.PARG Knockout MCF7 Cell Line is an MCF7 breast cancer cell line in which human PARG (Poly ADP-ribose glycohydrolase) has been genetically removed using CRISPR/Cas9 genome editing. This cell line has been validated by genomic sequencing and Western Blot.

Easy identification of cell death pathways in combination with other Dojindo’s kits, Multiple indicators can be measured in combination on the same plate, and Accurate plate assay without the need for washing.

The RayBio® Human TBMNK Flow Cytometry Kit is designed to determine the percentages and absolute counts of mature human lymphocyte subsets in peripheral whole blood (WB).

The RayBio® Human TBMNK Flow Cytometry Kit is designed to determine the percentages and absolute counts of mature human lymphocyte subsets in peripheral whole blood (WB).

Measure Gi signaling kinetics or activation with this live cell cAMP assay. This is a update to #X0200G, packaged in Big Sky BacMam providing a 3-4x increase in expression in cell types including HEK293 and CHO cells. BacMam also robustly transduces many iPSC and primary cultures, including neuronal and cardiac cells. The kit includes the cAMP sensor BacMam, 500mM sodium butyrate in H2O, and a positive control receptor and agonist (D2R BacMam and 2mM quinpirole in H2O). Other Montana Molecular tools including BacMam-packaged GPCRs can easily be co-expressed with this assay. 15mL and 30mL sizes are also available.