Chemicals & Small Molecules

BDP FL-PEG8-propargyl is a BDP FL linker containing a propargyl group. It can be reacted with terminal azide via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. It is a popular labeling dye used in Click Chemistry reactions. BDP FL-PEG8-propargyl is a bright and photostable thiol-reactive dye for protein labeling, peptide modification, and can replace fluorescein for microscopy. The hydrophilic PEG spacer arm increases water solubility, membrane permeability, and conjugation efficiency. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Amino-PEG24-acid, HCl salt is a bifunctional linker comprised of a terminal amino group that is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc, and an acid that can react with primary amine groups in the presence of activators such as HATU.

AMCA-PEG8-Propargyl is a AMCA dye that reacts with terminal azide via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. It is a popular labeling dye used in Click Chemistry reactions. It could be used as a quantum yield standard. Hydrophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

AMCA-PEG8-Azide is a fluroescent reagent with an azide group for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction. The hydrophilic PEG spacer arm increases water solubility, membrane permability, and conjugation efficiency. AMCA-PEG8-Azide is a popular blue fluorescent tagging molecule that has a maximal absorption of 345 nm and emission at 450 nm. This dye is used for protein and peptide labeing. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

1-(PEG-Amine)-2,3-(PEG4-Azide) is a branched PEG linker with a terminal amine that can be further derivatized for conjugation and two terminal azides that participate in click chemistry with linear alkynes, DBCO, and BCN.

Azide-PEG8-Val-Cit-PAB-MMAF serves as a linker-payload containing an azide click chemistry handle for click reactions with DBCO, BCN, and linear alkynes. MMAE is a synthetic antineoplastic agent which can be employed as a payload in the construction of ADCs (antibody-drug conjugates).The PEG chain enhances the water-solubility of the molecule.

Amine-PEG8-benzyl ester contains an amine, which can be further derivatized, and a benzyl ester, which can be used to protect carboxyl groups from reactions that can occur at amino groups and can be deprotected under catalytic hydrogenic conditions.

AMCA-PEG4-DBCO is a AMCA dye containing a reactive DBCO group and a hydrophilic PEG spacer arm with excitation/emission maximum of 345/450 nm. DBCO reacts with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalysts. It could be used as a quantum yield standard. Hydrophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG2-NHS ester serves as a heterobifunctional PEG linker comprised of a TCO click chemistry handle that readily reacts with tetrazine groups and NHS ester that directly and efficiently reacts with amine-bearing molecules. The PEG spacer imparts water solubility.