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Results for Chemicals & Small Molecules ( 99414 )
- Ref: T88443Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg
- From: €1,624.00
TAS2940 fumarate is a brain-penetrating, orally active, irreversible, and selective pan-ERBB inhibitor. It exhibits IC50 values of 5.6 nM, 2.1 nM, and 1.0 nM against wild-type HER2, HER2 V777L, and A775_G776insYVMA, respectively. TAS2940 fumarate is utilized for researching tumors characterized by abnormalities in HER2 and EGFR.
- From: €408.00
PF-07328948 is a branched chain ketone dehydrogenase kinase (BDK) inhibitor with oral biological activity. PF-07328948 can degrade branched chain ketone dehydrogenase (BCKDH) enzyme complex, thereby enhancing the catabolism of branched chain amino acids (BCAAs), and has potential inhibitory effects on heart failure, which can be used in heart failure related research.